Mycobacterium bovis infection at the interface between domestic and wild animals in Zambia
| Autor: | Mudenda B. Hang'ombe, Yukari Fukushima, Wigganson Matandiko, Akihiro Ishii, Musso Munyeme, Haruka Suzuki, Yasuhiko Suzuki, Chie Nakajima, Aaron S. Mweene |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Veterinary medicine
Cattle Diseases Zambia Strains Animals Wild Mycobacterium bovis Wildlife Polymerase Chain Reaction Bovine tuberculosis law.invention Tandem repeat law Kobus leche Kafuensis Animals lcsh:Veterinary medicine General Veterinary biology General Medicine biology.organism_classification veterinary(all) Transmission (mechanics) Antelopes Animals Domestic lcsh:SF600-1100 Cattle Tuberculosis Bovine Research Article |
| Zdroj: | BMC Veterinary Research BMC Veterinary Research, Vol 8, Iss 1, p 221 (2012) |
| ISSN: | 1746-6148 |
| Popis: | Background In Zambia, the presence of bovine tuberculosis in both wild and domestic animals has long been acknowledged and mutual transmission between them has been predicted without any direct evidence. Elucidation of the circulating Mycobacterium bovis strains at wild and domestic animals interphase area in Zambia, where bovine tuberculosis was diagnosed in wildlife seemed to be important. Results A PCR identified 15 and 37 M. bovis isolates from lechwe and cattle, respectively. Spoligotype analysis revealed that M. bovis strains from lechwe and cattle in Kafue basin clustered into a major node SB0120, where isolates outside the Kafue basin clustered into different nodes of SB0131 and SB0948. The comparatively higher variety of strains in cattle compared to lechwe elucidated by Mycobacterial Interspersed Repetitive Units–Variable Number Tandem Repeats analyses are consistent with cattle being the probable source of M. bovis in wild and domestic animals interphase area in Zambia. Conclusions These results provide strong evidence of M. bovis strains transfer between cattle and lechwe, with the latter having developed into a sylvatic reservoir host. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink