Effects of pregnancy and lactation on bone mineral density, and their relation to the serum calcium, phosphorus, calcitonin and parathyroid hormone levels in rats

Autor: Ibrahim Sahin, E. Gonen, Murat Ozbek, Yalim Ates, Saim Yologlu, Emrah Kovalak
Rok vydání: 2005
Předmět:
Zdroj: Journal of Endocrinological Investigation. 28:322-326
ISSN: 1720-8386
0391-4097
DOI: 10.1007/bf03347197
Popis: The aim of this study was to evaluate the net changes in bone mineral density (BMD) during the reproductive cycle, and their relation with changes in serum calcium (Ca), phosphorus (P), PTH and calcitonin levels in rats. Twenty-seven female Wistar rats were included in this study. They were divided into three groups as pregnant, lactating and control groups. BMDs of lumbar vertebrates, femoral and tibial bones, and Ca, P, calcitonin and PTH levels were measured at the end of pregnancy, at the end of lactation and in nulliparous controls. In the pregnant group, the BMDs of rats were significantly higher in lumbar vertebrates, femoral and tibia bones than those of the control group (p
Databáze: OpenAIRE