Inactivation of porcine epidemic diarrhea virus with electron beam irradiation under cold chain conditions

Autor: Yan Liu, Yang Shao, Lu Wang, Weilai Lu, Shihua Li, Diandou Xu, Yu Vincent Fu
Rok vydání: 2022
Předmět:
Zdroj: Environmental Technology & Innovation. 27:102715
ISSN: 2352-1864
DOI: 10.1016/j.eti.2022.102715
Popis: The many instances of COVID-19 outbreaks suggest that cold chains are a possible route for the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, owing to the low temperatures of cold chains, which are normally below 0 °C, there are limited options for virus inactivation. Here, high-energy electron beam (E-beam) irradiation was used to inactivate porcine epidemic diarrhea virus (PEDV) under simulated cold chain conditions. This coronavirus was used as a surrogate for SARS-CoV-2. The possible mechanism by which high-energy E-beam irradiation inactivates PEDV was also explored. An irradiation dose of 10 kGy reduced the PEDV infectious viral titer by 1.68-1.76 log
Databáze: OpenAIRE