Accuracy of a Novel Noninvasive Transdermal Continuous Glucose Monitor in Critically Ill Patients
| Autor: | Stanley A. Nasraway, Gail L. Kongable, My-Quyen Trieu, Keith Krystyniak, Ann Marie Melanson, Nicole M. Saur, Wayne Menzie, Hurley James P, Michael R. England, Jason Berlin |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Blood Glucose Male medicine.medical_specialty Critical Illness Endocrinology Diabetes and Metabolism Biomedical Engineering Bioengineering Biosensing Techniques Hypoglycemia Stress hyperglycemia law.invention Interstitial fluid law Diabetes mellitus Intensive care Internal Medicine medicine Humans Adverse effect Aged Monitoring Physiologic Aged 80 and over business.industry Reproducibility of Results Original Articles Middle Aged medicine.disease Intensive care unit Surgery Cardiac surgery Hyperglycemia Anesthesia Female business |
| Zdroj: | Journal of Diabetes Science and Technology. 8:945-950 |
| ISSN: | 1932-2968 |
| Popis: | Background: Stress hyperglycemia and hypoglycemia are associated with increased morbidity and mortality in the critically ill. Intermittent, random blood glucose (BG) measurements can miss episodes of hyper- and hypoglycemia. The purpose of this study was to determine the accuracy of the Symphony® continuous glucose monitor (CGM) in critically ill cardiac surgery patients. Methods: Fifteen adult cardiac surgery patients were evaluated immediately postoperatively in the intensive care unit. Prelude® SkinPrep prepared the skin and a sensor was applied to 2 test sites on each subject to monitor interstitial fluid glucose. Reference BG was sampled at 30- to 60-minute intervals. The skin at the test sites was inspected for adverse effects. Accuracy of the retrospectively analyzed CGM data relative to reference BG values was determined using continuous glucose-error grid analysis (CG-EGA) and mean absolute relative difference (MARD). Results: Using 570 Symphony CGM glucose readings paired with reference BG measurements, CG-EGA showed that 99.6% of the readings were within zones A and B. BG measurements ranged from 73 to 251 mg/dL. The MARD was 12.3%. No adverse device effects were reported. Conclusions: The Symphony CGM system is able to safely, continuously, and noninvasively monitor glucose in the transdermal interstitial fluid of cardiac surgery intensive care unit patients with accuracy similar to that reported with other CGM systems. Future versions of the system will need real-time data analysis, fast warm-up, and less frequent calibrations to be used in the clinical setting. |
| Databáze: | OpenAIRE |
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