Syndrome sérotoninergique consécutif à l'association d'escitalopram et de cyclosporine chez une patiente de 84 ans
| Autor: | Yasmine Hasso, Pierre Olivier Lang, Nicole Barbara Vogt-ferrier, Henriette Hilleret |
|---|---|
| Jazyk: | francouzština |
| Rok vydání: | 2008 |
| Předmět: |
medicine.medical_specialty
Serotonin reuptake inhibitor Immunosuppressive Agents/adverse effects Serotonin Syndrome/*chemically induced Citalopram Gastroenterology Serotonin syndrome Drug Administration Schedule Internal medicine mental disorders Internal Medicine medicine Escitalopram Humans Serotonin Uptake Inhibitors Citalopram/*adverse effects Fever/chemically induced Delirium/chemically induced Aged 80 and over Cyclosporine/*adverse effects business.industry Discontinuation Endocrinology Treatment Outcome Drug Therapy Combination Female Serotonin Serotonin Uptake Inhibitors/adverse effects medicine.symptom Reuptake inhibitor business medicine.drug |
| Zdroj: | Revue de médecine interne, Vol. 29, No 7 (2008) pp. 583-586 |
| ISSN: | 0248-8663 |
| Popis: | Due to the stimulation of central and peripheral 5-hydroxytryptamine receptors, the serotonin syndrome is a potentially lethal situation. The large variety of its clinical manifestations leads to a difficult diagnosis. We describe the case of a serotonin syndrome induced by the combined escitalopram and cyclosporine administration. An 84-year-old woman was hospitalized with a history of delirium associated with hyperthermia. The diagnosis of serotonin syndrome was suspected with the combination of the clinical features: the absence of infection, the selective serotonin reuptake inhibitor administration, and the absence of other metabolic and cerebral aetiology. After the discontinuation of escitalopram, the patient's condition improved rapidly. This report is a reminder of the clinical and pharmacological features of the serotonin syndrome from a recent literature review. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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