Is digital rectal examination still necessary in the early detection of prostate cancer?
| Autor: | David Mulvin, D. M. Quinlan, M. R. Quinlan, S. Teahan |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
Male medicine.medical_specialty PSA Measurement Urology Early detection Prostate cancer Prostate Biopsy medicine Humans Aged Digital Rectal Examination Retrospective Studies Ultrasonography Aged 80 and over medicine.diagnostic_test business.industry Prostatic Neoplasms Retrospective cohort study General Medicine Rectal examination Middle Aged Prostate-Specific Antigen medicine.disease Prostate-specific antigen medicine.anatomical_structure business |
| Zdroj: | Irish Journal of Medical Science. 176:161-163 |
| ISSN: | 1863-4362 0021-1265 |
| Popis: | PSA measurement is important in prostate cancer detection. However, applying cut-off values of4 ng/ml as indication for biopsy misses 20-30% of tumours.To determine the number of patients with prostate cancer and normal age-related PSA, referred for TRUS biopsy due to abnormal DRE alone.We reviewed patients referred for biopsy over 12 months. Indication for biopsy included abnormal PSA, abnormal DRE, or both.Four-hundred and sixty-five (465) TRUS biopsies were performed, 209 were positive. Of the 183 (183/209) positive on whom complete data were available, 4 (2.2%) had a normal age-related PSA but an abnormal DRE.Metastatic prostate cancer remains incurable. Therefore detection of organ-confined and potentially curable disease, is crucial. Though PSA has led to earlier detection, this study emphasises the importance of clinical examination, illustrating a normal PSA cannot eliminate the possibility of cancer. DRE and PSA should be interpreted as being collaborative, not competitive. |
| Databáze: | OpenAIRE |
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