Evidence for Maintained Post-Encoding Memory Consolidation Across the Adult Lifespan Revealed by Network Complexity
Autor: | Rajesh K. Kana, Hillary B. Erwin, Sarah K. Letang, Ian M. McDonough |
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Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: |
Network complexity
Computer science fmri General Physics and Astronomy lcsh:Astrophysics 050105 experimental psychology Article 03 medical and health sciences default mode network 0302 clinical medicine Encoding (memory) lcsh:QB460-466 medicine 0501 psychology and cognitive sciences lcsh:Science Episodic memory resting state Default mode network medicine.diagnostic_test Resting state fMRI 05 social sciences aging network complexity multiscale entropy episodic memory Content-addressable memory lcsh:QC1-999 Memory consolidation lcsh:Q Functional magnetic resonance imaging Neuroscience consolidation 030217 neurology & neurosurgery lcsh:Physics |
Zdroj: | Entropy, Vol 21, Iss 11, p 1072 (2019) Entropy Volume 21 Issue 11 |
ISSN: | 1099-4300 |
Popis: | Memory consolidation is well known to occur during sleep, but might start immediately after encoding new information while awake. While consolidation processes are important across the lifespan, they may be even more important to maintain memory functioning in old age. We tested whether a novel measure of information processing known as network complexity might be sensitive to post-encoding consolidation mechanisms in a sample of young, middle-aged, and older adults. Network complexity was calculated by assessing the irregularity of brain signals within a network over time using multiscale entropy. To capture post-encoding mechanisms, network complexity was estimated using functional magnetic resonance imaging (fMRI) during rest before and after encoding of picture pairs, and subtracted between the two rest periods. Participants received a five-alternative-choice memory test to assess associative memory performance. Results indicated that aging was associated with an increase in network complexity from pre- to post-encoding in the default mode network (DMN). Increases in network complexity in the DMN also were associated with better subsequent memory across all age groups. These findings suggest that network complexity is sensitive to post-encoding consolidation mechanisms that enhance memory performance. These post-encoding mechanisms may represent a pathway to support memory performance in the face of overall memory declines. |
Databáze: | OpenAIRE |
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