Ability of the post-operative ALBI grade to predict the outcomes of hepatocellular carcinoma after curative surgery

Autor: Chih-Chi Wang, Yu-Chieh Tsai, Tsung-Hui Hu, Ming-Chao Tsai, Yueh-Wei Liu, Chien-Hung Chen, Wei-Ru Cho, Chee-Chien Yong, Chih-Che Lin, Yi-Ju Wu, Chao-Hung Hung, Kuang-Den Chen
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
ISSN: 2045-2322
DOI: 10.1038/s41598-020-64354-0
Popis: The albumin-bilirubin (ALBI) grade has been validated as a significant predictor for hepatocellular carcinoma (HCC). However, there is little information about the impact of postoperative ALBI grade in patients with HCC who are undergoing liver resection. We enrolled 525 HCC patients who received primary resection from April 2001 to March 2017. The impact of the pre- and post-operative ALBI grades on overall survival (OS) and recurrence-free survival (RFS) were analyzed by multivariate analysis. During the follow-up period (mean, 65 months), 253 (48.1%) patients experienced recurrence, and 85 (16.2%) patients died. Multivariate analysis revealed that diabetes mellitus (DM) (p = 0.011), alpha-fetoprotein levels (AFP) (p p = 0.008), liver cirrhosis (p p p = 0.006), DM (p = 0.002), AFP (p = 0.027), and ALBI grade at the first year after resection (p
Databáze: OpenAIRE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje