Evaluation of serum immunoglobulin concentrations in the perinatal period by use of a standardized method of measurement

Autor: George W. Brumley, J. Benjamin Younger, Rebecca H. Buckley
Rok vydání: 1969
Předmět:
Zdroj: The Journal of Pediatrics. 75:1143-1148
ISSN: 0022-3476
DOI: 10.1016/s0022-3476(69)80370-7
Popis: Concentrations of IgG, IgA, and IgM were quantitatively estimated by single radial diffusion in 133 maternal cord serum pairs and in 84 newborn sera. The antisera and reference standards were prepared in this laboratory and the IgM antibody-agar plates for cord and newborn sera contained the optimal amount of antiserum for IgM concentrations usually found at those ages. All data were converted to logarithms for statistical analyses. The ±2 standard deviation limits obtained for cord and newborn serum IgM concentrations were found to be sufficiently narrow to permit ready detection of deviations from the norm by standard statistical tests of significance.
Databáze: OpenAIRE