A novel HLA-B allele, HLA-B*35:279, identified by sequencing-based typing in a Czech patient
| Autor: | Martin Petrek, V. Siffnerova, Z. Ambruzova, Luděk Raida, Ivana Skoumalova, Nikola Königova, J. Onderkova, M. Vrana, Frantisek Mrazek |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Immunology Biology 03 medical and health sciences 0302 clinical medicine Antigen Valine Genetics HLA-B Antigens Humans Typing Allele Molecular Biology Gene Alleles Genetics (clinical) Czech Republic Base Sequence Histocompatibility Testing General Medicine Molecular biology HLA-B 030104 developmental biology Amino Acid Substitution Isoleucine 030215 immunology |
| Zdroj: | International Journal of Immunogenetics. 43:246-248 |
| ISSN: | 1744-3121 |
| DOI: | 10.1111/iji.12276 |
| Popis: | The identification of a novel HLA-B*35:279 allele in a Czech patient is described. This allele is identical to the B*35:03:01 variant except the G/A nucleotide exchange at position 652 of the HLA-B gene that corresponds to the amino acid substitution from valine to isoleucine in alpha 3 domain of the HLA-B antigen. |
| Databáze: | OpenAIRE |
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