| Autor: |
Benjamin E. Konwaler, Thomas H. Brem |
| Rok vydání: |
1955 |
| Předmět: |
|
| Zdroj: |
American Heart Journal. 50:476-481 |
| ISSN: |
0002-8703 |
| DOI: |
10.1016/0002-8703(55)90169-1 |
| Popis: |
1. 1. Emetine hydrochloride when given in the usual therapeutic doses frequently produces definite but not dangerous effects on the heart. 2. 2. Individual tolerance to emetine toxicity is extremely variable. The human lethal dose appears to be about 20 mg./kg. of body weight. 3. 3. Long or frequently repeated courses of emetine may constitute a distinct hazard. An illustrative case of emetine-induced myocarditis with death and pathologic findings is described. 4. 4. Although chloroquine should replace emetine in the therapy of hepatic amebiasis, the latter will still be useful in other forms of extraintestinal amebiasis. The potential hazards of its use should therefore be recognized. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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