Measurement of arterial stiffness and vascular aging in community pharmacies—The ASINPHAR@2action project
| Autor: | Ana Luísa Pinto, Maria João Mendes, Sonja Gose, Mariana Rosa, Ema Paulino, Telmo Pereira, Sofia Maximiano, Joana Brito, Johannes Risse, Patrícia Soares |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Aging
medicine.medical_specialty Endocrinology Diabetes and Metabolism Blood Pressure 030204 cardiovascular system & hematology 03 medical and health sciences Vascular Stiffness 0302 clinical medicine Quality of life Diabetes mellitus Internal medicine Internal Medicine medicine Humans 030212 general & internal medicine Pulse wave velocity Subclinical infection Pharmacies business.industry medicine.disease medicine.anatomical_structure Blood pressure Hypertension Cohort Vascular resistance Arterial stiffness Arterial Stiffness Cardiology and Cardiovascular Medicine business |
| Zdroj: | J Clin Hypertens (Greenwich) |
| ISSN: | 1751-7176 1524-6175 |
| DOI: | 10.1111/jch.13554 |
| Popis: | The ASINPHAR@2action project aims at raising awareness to arterial stiffness (AS) and early vascular aging (EVA) through a community pharmacy–based intervention. This preliminary analysis is focused on the analysis of the proportion of participants with increased AS and the identification of its main determinants. We performed an observational cross‐sectional study of participants enrolled in 11 community pharmacies in Portugal, between April and November 2017. Blood pressure (BP) and arterial function parameters were measured with a validated device. Clinical and demographic information was gathered, as well as the estimation of global cardiovascular risk, health‐related quality of life, and dietary profile. Cholesterol and glycaemia were taken from a recent laboratory bulletin. The cohort includes 658 participants with a mean age of 57.3 ± 16.3 years, 66% women. Brachial BP was 126.6 ± 16.4 mm Hg and 79.9 ± 11.5 mm Hg, and central BP was 115.8 ± 15.4 mm Hg and 81.2 ± 11.6 mm Hg, respectively, for systolic and diastolic BP. Mean pulse wave velocity (PWV) was 8.5 ± 2.3 m/s, and the augmentation index was 23.6 ± 15.6%. The proportion of participants with increased AS was 19.8%. The overall best‐fitting model for AS included age, gender, aortic PP, visceral fat, HDL cholesterol, AIx@75, total vascular resistance, hypertension, and diabetes, corresponding to an AUC of 0.910 (CI: 0.883, 0.937; P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|