| Autor: |
Khadidja Y. Ismailova, Mohammadreza Majidi, Ulduz Hashimova |
| Jazyk: |
ruština |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Вестник Московского государственного областного университета: Серия: Естественные науки, Iss 4, Pp 46-55 (2017) |
| ISSN: |
2310-7189 |
| Popis: |
The effect of fluoxetine on memory processes is studied by using the model of the conditioned reflex of passive avoidance (CRPA) in male Wistar rats with a different phenotype of the nervous system and a different ratio of the activity of monoaminergic (MA) systems of the brain. High rates of saving of CRPA against the background of administration of a psychopharmacological preparation are found in convulsively-tolerant rats, expressed in an increase in the total time of residence of animals in a safe camera compartment, in an increase in a search activity and a low vegetative index, as well as in an increase in the number of rats with the skill kept. Unlike the control group, convulsive-sensitive rats show a decrease in these parameters. It is assumed that the individual animal's sensitivity to the action of psychopharmacological fluoxetine drug and the direction of effects caused by it in the mnemonic processes are due to the different initial ratio of activity of MA-systems of different brain structures. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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