The essential features and modes of bacterial polar growth
Autor: | Todd A. Cameron, Patricia Zambryski, John R. Zupan |
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Rok vydání: | 2015 |
Předmět: |
Microbiology (medical)
Cell division Agrobacterium Peptidoglycan Microbiology Mycobacterium chemistry.chemical_compound Bacterial Proteins Virology Actinomycetales Botany FtsZ Alphaproteobacteria Bacteria biology Cell Cycle fungi biology.organism_classification Rhizobiales Cytoskeletal Proteins Infectious Diseases chemistry Evolutionary biology biology.protein FtsA Cell Division |
Zdroj: | Trends in Microbiology. 23:347-353 |
ISSN: | 0966-842X |
DOI: | 10.1016/j.tim.2015.01.003 |
Popis: | Polar growth represents a surprising departure from the canonical dispersed cell growth model. However, we know relatively little of the underlying mechanisms governing polar growth or the requisite suite of factors that direct polar growth. Underscoring how classic doctrine can be turned on its head, the peptidoglycan layer of polar-growing bacteria features unusual crosslinks and in some species the quintessential cell division proteins FtsA and FtsZ are recruited to the growing poles. Remarkably, numerous medically important pathogens utilize polar growth, accentuating the need for intensive research in this area. Here we review models of polar growth in bacteria based on recent research in the Actinomycetales and Rhizobiales, with emphasis on Mycobacterium and Agrobacterium species. |
Databáze: | OpenAIRE |
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