Canine Cutaneous and Subcutaneous Soft Tissue Sarcoma: An Evidence-Based Review of Case Management
| Autor: | Jamie Haddad, Lisa G. Barber, Anita Soucy, Ann E. Hohenhaus, Matthew Palmisano, Jennifer L. Kelsey, John Farrelly |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Soft Tissue Neoplasm 040301 veterinary sciences medicine.medical_treatment Antineoplastic Agents Soft Tissue Neoplasms Metastasis 0403 veterinary science 03 medical and health sciences Dogs 0302 clinical medicine Pharmacotherapy Biopsy medicine Animals Dog Diseases Small Animals Evidence-Based Medicine medicine.diagnostic_test business.industry Soft tissue sarcoma Soft tissue Sarcoma 04 agricultural and veterinary sciences medicine.disease Surgery Radiation therapy 030220 oncology & carcinogenesis business |
| Zdroj: | Journal of the American Animal Hospital Association. 52:77-89 |
| ISSN: | 1547-3317 0587-2871 |
| Popis: | Canine cutaneous and subcutaneous soft tissue sarcomas (STS) account for 20.3% of malignant neoplasms of the skin. This article makes recommendations for the diagnosis, treatment, and follow-up in dogs with STS, using evidence-based medicine concepts. Although our review of the literature on the management of canine STS found many of the studies to be less than rigorous, board-certified specialists in internal medicine, surgery, pathology, oncology, and radiation oncology were able to make several recommendations based on the literature review: cytology and biopsy are important for presurgical planning; wide (>3 cm margins) surgical excision decreases the likelihood of tumor recurrence; the use of a histologic grading scale is useful in predicting biologic behavior; and, in select cases, chemotherapy and radiation therapy may be beneficial adjunct treatments to surgical excision. More research is necessary to determine minimum size of surgical margins, the impact of radiation therapy on incompletely resected tumors, the ideal chemotherapy protocol for high grade STS, and the optimal methods of monitoring dogs for tumor recurrence and metastasis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|