Control of developmental gene expression by cell-to-cell interactions in Myxococcus xanthus
| Autor: | M G Cull, R E Gill |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
Spores
Bacterial Genetics Regulation of gene expression Mutation biology Genetic Complementation Test fungi Mutant DNA Recombinant lac operon medicine.disease_cause biology.organism_classification Microbiology Complementation Gene Expression Regulation Genes Bacterial Gene expression medicine Myxococcales Promoter Regions Genetic Myxococcus xanthus Molecular Biology Gene Research Article |
| Zdroj: | Journal of Bacteriology. 168:341-347 |
| ISSN: | 1098-5530 0021-9193 |
| DOI: | 10.1128/jb.168.1.341-347.1986 |
| Popis: | The ssbA mutants of Myxococcus xanthus behave as if they are unable to produce a cell-to-cell signal required for normal development. They are unable to form fruiting bodies or spores on developmental medium. They do sporulate, however, if allowed to develop in mixtures with wild-type cells. Fusions of developmentally induced promoters of M. xanthus to the Escherichia coli lacZ gene were used to characterize the effect of the ssbA mutations on developmental gene expression. Each of the five independent fusions tested was found to be dependent upon the ssbA+ allele for full expression. The ssbA mutants were able to express each of these fusions if the mutants were allowed to develop in mixtures with wild-type (Lac-) cells. These results cannot be explained on the basis of genetic exchange. The data are consistent with regulation of gene expression mediated by cell-to-cell interactions. |
| Databáze: | OpenAIRE |
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