Thyroid Function and Anti-TPO Antibody Status among Tribal Perimenopausal Women Near Bengaluru, Karnataka, India

Autor: Swapna Jaswanth, K. S. Manjula, Reena R, Smr Usha
Rok vydání: 2020
Předmět:
Zdroj: Journal of Clinical and Diagnostic Research, Vol 14, Iss 10, Pp BC28-BC32 (2020)
ISSN: 2249-782X
Popis: Introduction: Higher prevalence of thyroid diseases are noted with increasing age. Symptoms of thyroid disorders often develop so insidiously, that they go unnoticed and there is also the risk of being misinterpreted for menopausal symptoms. Present study was executed in view of paucity of data regarding thyroid disorders among tribal perimenopausal age group and there was a need for timely intervention of this chronic non-communicable disorder among these women. Aim: To determine the thyroid function and anti-Thyroid Peroxidase Antibody (anti-TPO Ab) status among the tribal perimenopausal women. Materials and Methods: A descriptive, cross-sectional study was conducted for a period of six months from July 2017 to December 2017 among perimenopausal women in the age group of 40-55 years residing at Hakki Pikki Tribal Colony near Bengaluru, Karnataka, India. Thyroid Stimulating Hormone (TSH), Total T3 (Total Tri iodothyronine), Total T4(Total Tetraidiodothyronine) and anti-TPO antibody levels were estimated by Chemiluminescence Immuno Assay (CLIA). Data was analysed using Open Epi software to find out Mean±SD, p-value (Student’s t-test with significance set at p30 IU/mL) was found in 14 (34.14%) women amongst 41 perimenopausal subjects. Raised anti-TPO Ab was observed in all the 3 (100%) SCH women and 11 (26.82%) euthyroid women. Significant difference (p
Databáze: OpenAIRE