Oesophageal Manometry in Experimental Pigs: Methods and Initial Experience
| Autor: | Věra Radochová, Jan Bures, Jaroslav Květina, Ilja Tachecí, Marcela Kopáčová, Stanislav Rejchrt |
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| Rok vydání: | 2015 |
| Předmět: |
Male
Experimental pigs Oesophageal manometry Manometry General Anaesthesia Sus scrofa lcsh:Medicine Anesthesia General Esophageal Sphincter Lower Esophagus Swallowing Pressure medicine Animals Lower oesophageal sphincter General anaesthesia business.industry lcsh:R Oesophageal peristalsis General Medicine Oesophageal Manometry medicine.anatomical_structure Anesthesia Models Animal Female business |
| Zdroj: | Acta Medica, Vol 58, Iss 4, Pp 131-134 (2016) |
| ISSN: | 1805-9694 1211-4286 |
| Popis: | The aim of this study project was to prepare our own method of porcine oesophageal manometry. Ten mature experimental pigs entered the study. Conventional water-perfused system was decided for manometry. Porcine resting and relaxed pressures of the lower oesophageal sphincter are fully comparable with healthy human subjects. Evocable swallowing is doable and oesophageal peristalsis is quantifiable. Basic manometric parameters were different in male and female animals. Oesophageal manometry in experimental pigs is feasible. Porcine oesophageal manometry will be usable for preclinical studies in future. |
| Databáze: | OpenAIRE |
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