Polymer-Supported Triacetoxyborohydride: A Novel Reagent of Choice for Reductive Amination

Autor:	Owen W. Gooding, Sukanta Bhattacharyya, Sunil Rana, Jeff Labadie
Rok vydání:	2003
Předmět:	Reaction conditions Primary (chemistry) Chemistry Organic Chemistry General Medicine Biochemistry Reductive amination Combinatorial chemistry Reagent Drug Discovery Organic chemistry Reactivity (chemistry) Amination Polymer supported
Zdroj:	ChemInform. 34
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.200340063
Popis:	A novel polymer-supported triacetoxyborohydride reagent for reductive amination of aldehydes and ketones is reported. The bound reagent was found to be shelf-stable and provided broad scope and reactivity in reductive amination reactions under mild reaction conditions. Streamlined protocols for its application in reductive amination reactions using both primary and secondary amines are described.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72433dd337d9dcd576cc8c196c509a6a https://doi.org/10.1002/chin.200340063 Zobrazit plný text záznamu Plný text