Familial adult T-cell leukemia
| Autor: | Kazunari Yamaguchi, Yuichi Miyamoto, Kiyoshi Takatsuki, Tatsuomi Yasaka, Teruto Koga, Hiromichi Nishimura, Ippei Ohya, Minoru Morimatsu, Tadashi Motoori |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Adult
Male Cancer Research T-Lymphocytes viruses T-cell leukemia Antibodies Viral Deltaretrovirus Virus Antigen Bone Marrow immune system diseases hemic and lymphatic diseases medicine Humans Leukemia biology Transmission (medicine) business.industry medicine.disease Pedigree Oncology Immunology biology.protein Lymph Nodes Antibody business Horizontal transmission |
| Zdroj: | Cancer. 55:181-185 |
| ISSN: | 1097-0142 0008-543X |
| DOI: | 10.1002/1097-0142(19850101)55:1<181::aid-cncr2820550128>3.0.co;2-e |
| Popis: | Two siblings who developed adult T-cell leukemia (ATL) are presented. The patient and 7 of 26 healthy family members examined had the serum antibodies against ATL-associated antigens (ATLA). This family study shows that two main routes of transmission of human T-cell leukemia virus (HTLV) may be involved: one is the route from parents to children and the other is horizontal transmission among spouses, especially from husband to wife; the anti-ATLA-positive family is considered to be a high-risk group for ATL. |
| Databáze: | OpenAIRE |
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