Analysis of the Risk Factors for Mortality in Adult COVID-19 Patients in Wuhan: A Multicenter Study
| Autor: | Min Wang, Wei Long, Wei Zhou, Shipei Wang, Haibo Xu, Yihui Huang, Man Li, Zeming Liu, Biao Cheng, Danyang Chen, Mengqi Tu, Lin Zhou, Sichao Chen, Wen Zeng, Wei Tong, Meng Wu, Liang Guo, Aiping Deng |
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| Rok vydání: | 2020 |
| Předmět: |
Wuhan
medicine.medical_specialty Multivariate statistics Coronavirus disease 2019 (COVID-19) Disease 010502 geochemistry & geophysics 01 natural sciences Odds 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Internal medicine medicine risk factors 030212 general & internal medicine Stage (cooking) Original Research 0105 earth and related environmental sciences lcsh:R5-920 Creatinine SARS-CoV-2 business.industry Proportional hazards model COVID-19 Outbreak General Medicine mortality chemistry Medicine lcsh:Medicine (General) business |
| Zdroj: | Frontiers in Medicine Frontiers in Medicine, Vol 7 (2020) |
| ISSN: | 2296-858X |
| DOI: | 10.3389/fmed.2020.00545 |
| Popis: | Objectives: An outbreak of coronavirus disease (COVID-19) in 2019 in Wuhan, China, has spread quickly worldwide. However, the risk factors associated with COVID-19-related mortality remain controversial.Methods: A total of 245 adult patients with laboratory-confirmed COVID-19 from two centers were analyzed. Chi-square, Fisher's exact, and the Mann-Whitney U-tests were used to compare the clinical characteristics between the survivors and non-survivors. To explore the risk factors associated with in-hospital death, univariable and multivariable cox regression analyses were used.Results: Of the 245 patients included in this study, 23 (9.4%) died in the hospital. The multivariate regression analysis showed increased odds of in-hospital deaths associated with age, D-dimer levels >1,000 ng/L, platelet count |
| Databáze: | OpenAIRE |
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