Ovarian incision enhances folliculogenesis: A rat model

Autor: Selin Ozaltin, Bahar Yuksel, Mehmet Resit Asoglu, Faruk Buyru, Fatma Tokat, Murat Dogan, Mete Güngör, Ercan Bastu, Kerem Cavit Kayhan, Ozguc Takmaz
Rok vydání: 2020
Předmět:
Zdroj: Journal of Obstetrics and Gynaecology Research. 46:2043-2049
ISSN: 1447-0756
1341-8076
Popis: AIM To determine whether performing incision on the surface of the ovarian cortex in rats advances follicular development. METHODS Five to seven separate superficial incisions were performed on the surface of right ovaries of 6-7-month-old albino Wistar rats. Daily 40 IU of gonadotropins were administered for 14 days. On the 15th day, both ovaries of the rats were removed. The right (incised) ovaries were compared with the contralateral ovaries in terms of ovary's weight, numbers of primordial, primary, secondary and antral follicles, their mean percentages and mean Ki-67 proliferation indices. RESULTS A total of 22 ovaries were evaluated, with 11 right ovaries (incised) and 11 left ovaries (non-incised). The mean weight of ovaries was greater in the right ovaries than in the left ovaries; however, no statistical difference was found between them (0.77 ± 1.22 vs. 0.22 ± 0.08 gr, P = 0.159). The numbers of secondary and antral follicle were statistically higher in the right ovaries than in the left ovaries (4.4 ± 1.5 vs. 2.1 ± 1.6, P = 0.003 and 18.6 ± 8.7 vs. 11.3 ± 7.5, P = 0.046, respectively). The right ovaries also significantly differed from the left ovaries in terms of mean percentages of primordial and antral follicles (P
Databáze: OpenAIRE
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