Identification of ethanolamine in rat and gerbil brain tissue extracts by NMR spectroscopy
| Autor: | A G Swanson, Steven Williams, G B Fox, J B Clark, K L Allen, K.D. Sales, S C Smart, G T G Swayne, M J Newman |
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| Rok vydání: | 1994 |
| Předmět: |
Male
Magnetic Resonance Spectroscopy Biology Gerbil Brain Ischemia Rats Sprague-Dawley chemistry.chemical_compound Ethanolamine medicine.artery medicine Animals Radiology Nuclear Medicine and imaging Perchloric acid Spectroscopy Brain Chemistry Tissue Extracts Extraction (chemistry) Nuclear magnetic resonance spectroscopy In vitro Rats Disease Models Animal Biochemistry chemistry Ethanolamines Cell culture Middle cerebral artery Molecular Medicine Protons Gerbillinae |
| Zdroj: | NMR in Biomedicine. 7:356-365 |
| ISSN: | 1099-1492 0952-3480 |
| DOI: | 10.1002/nbm.1940070806 |
| Popis: | Some NMR resonances which have previously been observed but not identified in mammalian brain tissue extracts have been shown to arise from ethanolamine. This conclusion is drawn from a systematic study of the perchloric acid extracts of rodent brain tissue in which several NMR experiments were used to assign the peaks unambiguously. The extraction procedure used in this work gave samples with highly reproducible spectra, and ethanolamine was observed in all our extract samples. A localized increase in the concentration of ethanolamine was seen in the spectra of extracts produced from a cerebral infarct induced by occlusion of the middle cerebral artery in the rat. |
| Databáze: | OpenAIRE |
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