Increased myocardial ultrasonic reflectivity is associated with extreme hypertensive left ventricular hypertrophyA tissue characterization study in humans
| Autor: | L Talarico, Eugenio Picano, Vitantonio Di Bello, Alessandra R. Lucarini, Marco Paterni, Roberto Pedrinelli |
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| Rok vydání: | 1998 |
| Předmět: |
Adult
Male medicine.medical_specialty Heart disease Left ventricular hypertrophy Muscle hypertrophy Internal medicine Internal Medicine medicine Humans Scattering Radiation Pericardium Aged business.industry Ultrasound Tissue characterization Middle Aged medicine.disease Reflectivity medicine.anatomical_structure Echocardiography Hypertension Cardiology Female Hypertrophy Left Ventricular Ultrasonic sensor business |
| Zdroj: | American Journal of Hypertension. 11:1442-1449 |
| ISSN: | 0895-7061 |
| DOI: | 10.1016/s0895-7061(98)00148-4 |
| Popis: | We assessed myocardial reflectivity pattern in a large spectrum of left ventricular mass values, covering the extremes from absent to severe myocardial hypertensive hypertrophy. Quantitatively assessed ultrasonic backscatter is an index of ultrasonic tissue characterization directly related to the morphometrically evaluated collagen content in humans. We enrolled 88 essential hypertensives. With an echo prototype implemented in our Institute, integrated values of the radiofrequency signal of myocardial walls were obtained and normalized for those of the pericardium (Integrated Backscatter Index, IBI, %). Left ventricular mass index (LVMI) was measured by Devereux formula. There was a weak correlation between septal IBI and LVMI (r = 0.35; P.001). On the basis of LVMI values, three groups of hypertensives were identified, with absent (Group I, n = 23; LVMI125 g/m2), mild to moderate (Group II, n = 44; LVMI from 125 to 174 g/m2), or severe (Group III, n = 21; LVMI175 g/m2) left ventricular hypertrophy. The Integrated Backscatter Index in the septum was lower in patients of Group I (IBI = 23.3% +/- 3.6%) and II (IBI = 26.5 +/- 7.6; P = NS v Group I), in comparison with patients of Group III (IBI = 31.1 +/- 5.9; P.02 v II; P.0001 v I). An increased myocardial wall reflectivity is detectable only in the presence of extreme forms of hypertensive left ventricular hypertrophy. |
| Databáze: | OpenAIRE |
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