Associations between skeletal muscle mass index, nutritional and functional status of patients with oesophago-gastric cancer
Autor: | Ioannis Karavokyros, Irene Lidoriki, Maria Sotiropoulou, Michail Vailas, Eustratia Mpaili, Dimitrios Schizas, Evangelos P. Misiakos, Emmanouil Pikoulis, Theodoros Liakakos, Alexandros Papalampros |
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Rok vydání: | 2019 |
Předmět: |
Male
0301 basic medicine medicine.medical_specialty Endocrinology Diabetes and Metabolism Nutritional Status 030209 endocrinology & metabolism Muscle mass Protein-Energy Malnutrition Body Mass Index 03 medical and health sciences 0302 clinical medicine Stomach Neoplasms Weight loss Internal medicine Weight Loss Prevalence medicine Humans Muscle Strength General hospital Muscle Skeletal Aged 030109 nutrition & dietetics Nutrition and Dietetics Greece Hand Strength business.industry Malnutrition Cancer Middle Aged Physical Functional Performance Anthropometry medicine.disease Skeletal muscle mass Hospitalization Cross-Sectional Studies Nutrition Assessment Female Functional status medicine.symptom business |
Zdroj: | Clinical Nutrition ESPEN. 34:61-67 |
ISSN: | 2405-4577 |
Popis: | Cancer patients frequently suffer from disease-related malnutrition and functional decline. The aim of the current study is to investigate the association between traditional methods of nutritional assessment (unintentional weight loss, Patient Generated-Subjective Global Assessment, anthropometric measurements), functional assessment and muscle mass assessment in oesophago-gastric cancer patients prior to surgery.A cross-sectional study was performed in 108 consecutive patients with oesophageal and gastric cancer who were admitted for surgery in the First Department of Surgery, Laikon General Hospital, Athens, Greece. The assessment of muscle mass was based on preoperative Skeletal Muscle Mass Index (SMI) values. The assessment of malnutrition was based on the Patient Generated Subjective Global Assessment, whereas laboratory markers and anthropometric measurements were also recorded. Muscle strength and physical performance were evaluated by measuring patients' handgrip strength and gait speed respectively.76.8% of the study sample were severely malnourished and moderately or suspected of being malnourished, while the prevalence of low muscle mass was 49.1%. Age was significantly higher in low SMI patients compared to normal SMI individuals (67.2 ± 9.2 vs 60 ± 10.8, p 0.001). Albumin was significantly lower in low SMI compared to normal SMI patients, as well as BMI, mid-upper arm circumference, calf circumference and corrected mid arm muscle area. Moreover, malnourished patients exhibited higher rates of low muscle mass (57.8% vs 42.2%, p = 0.022) than well-nourished patients. SMI was also significantly correlated with patients' handgrip strength and gait speed.Low muscle mass is strongly correlated with malnutrition and should be taken into consideration when evaluating the nutritional status of patients with oesophago-gastric cancer. |
Databáze: | OpenAIRE |
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