Coupled plasma filtration adsorption improves hemodynamics in septic shock
| Autor: | Marilù Giacalone, Rocco Rago, Giacomo Giulio Baldi, Matteo Franchi, Francesco Forfori, Francesco Giunta, Ippolito Traupe |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male CPFA medicine.medical_specialty Mean arterial pressure Critical Care medicine.medical_treatment 030232 urology & nephrology Hemodynamics Reference range Critical Care and Intensive Care Medicine law.invention Plasma 03 medical and health sciences 0302 clinical medicine law Septic shock Internal medicine Hemofiltration medicine Humans Leukocytosis Lead (electronics) Aged Retrospective Studies Aged 80 and over Cytokines Multiple organ failure business.industry 030208 emergency & critical care medicine Middle Aged medicine.disease Shock Septic Intensive care unit Surgery Italy Cardiology Fluid Therapy Female Adsorption medicine.symptom business |
| Zdroj: | Journal of Critical Care. 33:100-105 |
| ISSN: | 0883-9441 |
| DOI: | 10.1016/j.jcrc.2016.02.005 |
| Popis: | Purpose Septic shock involves a dysregulation of the immune response to an infection. This may lead to hemodynamic dysfunction and multiple-organ failure. The main aim of this study was to evaluate the effect of coupled plasma filtration adsorption (CPFA) on the hemodynamic profile in patients with septic shock. Materials and methods We retrospectively analyzed data from 21 adult patients admitted to the intensive care unit with a diagnosis of septic shock, comparing data between pre-CPFA and post-CPFA treatment. They received a maximum of 5 cycles of treatment. Results Coupled plasma filtration adsorption treatment was associated with a significant increase of mean arterial pressure ( P P = .007), and renal improvement. In patients with leukocytosis or leucopenia, the leukocyte count was restored to a reference range of values. Conclusion Treatment with CPFA improves hemodynamic parameters in septic shock patients, ameliorating organ failure. |
| Databáze: | OpenAIRE |
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