Primary Small Cell Carcinoma of the Bladder: A Report of 25 Cases
| Autor: | Sonny L. Johansson, Goran Borghede, Sten Holmang |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Aged
80 and over Male medicine.medical_specialty Urinary bladder medicine.diagnostic_test Systemic chemotherapy business.industry Urology Incidence (epidemiology) Cancer Autopsy Disease Middle Aged medicine.disease Small-cell carcinoma Surgery medicine.anatomical_structure Urinary Bladder Neoplasms Biopsy medicine Humans Female Carcinoma Small Cell business Aged |
| Zdroj: | Journal of Urology. 153:1820-1822 |
| ISSN: | 1527-3792 0022-5347 |
| DOI: | 10.1016/s0022-5347(01)67320-8 |
| Popis: | Primary small cell carcinoma of the bladder is a rare condition with approximately 100 cases reported to date. An incidence of 0.7% small cell carcinoma was found in a total series of bladder tumors diagnosed in Western Sweden during a 2-year period. We describe 22 patients with primary small cell carcinoma followed to death or for at least 6 years. Three additional cases were diagnosed at autopsy. Of 18 patients with stages T2M0 to T4M0 cancer treated with locoregional therapy 5 (28%) had no evidence of disease after a median observation of 10 years (range 6 to 18) and 13 died of disease after 0.5 to 19 months (median 7.3). Two patients with metastatic disease were treated with systemic chemotherapy but died within 15 months. Two patients died shortly after the diagnostic biopsy. Our study and a review of the literature indicate that primary small cell carcinoma of the bladder is less aggressive than its pulmonary counterpart and that some patients can be cured by transurethral resection, or partial or radical cystectomy combined with radiotherapy. |
| Databáze: | OpenAIRE |
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