Enquiring beneath the surface: can a gene expression assay shed light into the heterogeneity among newborns with neonatal encephalopathy?

Autor:	Gemma Arca, Alfredo García-Alix, Miguel Alsina, Cristian Tebé, Marisol León, Soledad Alcántara, Rafael Balada, Alba-Aina Castells
Rok vydání:	2019
Předmět:	Male medicine.medical_specialty Peroxisome proliferator-activated receptor gamma Candidate gene Receptors CCR5 Chorioamnionitis Infant Newborn Diseases 03 medical and health sciences 0302 clinical medicine Sex Factors Hypothermia Induced Pregnancy 030225 pediatrics Internal medicine Gene expression medicine Humans HSP70 Heat-Shock Proteins Interleukin 8 Prospective Studies RNA Messenger Hypoxia Brain Whole blood business.industry Neonatal encephalopathy Gene Expression Profiling Interleukin-8 Infant Newborn medicine.disease Sexual dimorphism PPAR gamma Endocrinology Gene Expression Regulation Matrix Metalloproteinase 9 Toll-Like Receptor 8 Pediatrics Perinatology and Child Health Hypoxia-Ischemia Brain Female business 030217 neurology & neurosurgery
Zdroj:	Pediatric research. 88(3)
ISSN:	1530-0447
Popis:	BACKGROUND We aimed to assess whether a gene expression assay provided insights for understanding the heterogeneity among newborns affected by neonatal encephalopathy (NE). METHODS Analysis by RT-qPCR of the mRNA expression of candidate genes in whole blood from controls (n = 34) and NE (n = 24) patients at
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72182badd7074b141ceb7616e0878192 https://pubmed.ncbi.nlm.nih.gov/32746447 Zobrazit plný text záznamu Full text from SpringerLink