AQP8 and AQP9 expression in patients with polycystic ovary syndrome and its association with in vitro fertilization‑embryo transfer outcomes
| Autor: | Xianghui Zeng, Zhengfang Xiong, Huishu Liu, Binye Li, Xiaoyan Sha, Bing Li, Liyun Wang |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Cancer Research Pregnancy Ovarian cyst In vitro fertilisation endocrine system diseases business.industry medicine.medical_treatment Articles General Medicine medicine.disease Polycystic ovary female genital diseases and pregnancy complications Embryo transfer Andrology 03 medical and health sciences Pregnancy rate 030104 developmental biology 0302 clinical medicine Immunology and Microbiology (miscellaneous) 030220 oncology & carcinogenesis medicine Luteinizing hormone business Testosterone |
| Zdroj: | Experimental and Therapeutic Medicine. |
| ISSN: | 1792-1015 1792-0981 |
| DOI: | 10.3892/etm.2019.7592 |
| Popis: | The aim of the present study was to investigate aquaporin (AQP)8 and AQP9 expression in patients with polycystic ovary syndrome (PCOS) and its association with in vitro fertilization-embryo transfer (IVF-ET) outcomes. A total of 45 patients with PCOS undergoing IVF-ET (test group) and 50 patients with oviduct obstruction or ovarian cyst (control group) were assessed for the mRNA expression of AQP8 and AQP9 in ovarian tissues by reverse transcription-quantitative (RT-q)PCR. The levels of luteinizing hormone, anti-mullerian hormone and testosterone were determined, which were revealed to be significantly different between the two groups (P0.05). The pregnancy rate in patients with high AQP9 expression was higher than that in the low AQP9 expression group (P |
| Databáze: | OpenAIRE |
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