Patterns of clinicopathological features and outcome in epithelial ovarian cancer patients: 35 years of prospectively collected data
| Autor: | Tzyvia Rye, Fiona Nussey, K Herbert, Robert L Hollis, CS Herrington, A Irodi, Michael Churchman, Melanie Mackean, Charlie Gourley, Clare Bartos |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Optimal Debulking Population Kaplan-Meier Estimate Carcinoma Ovarian Epithelial Gastroenterology 03 medical and health sciences 0302 clinical medicine Internal medicine Ovarian carcinoma medicine Humans Registries Age of Onset Stage (cooking) education Neoplasm Staging Retrospective Studies Ovarian Neoplasms education.field_of_study 030219 obstetrics & reproductive medicine business.industry Obstetrics and Gynecology Histology Cytoreduction Surgical Procedures Debulking medicine.disease Progression-Free Survival Serous fluid Scotland Female Neoplasm Grading Ovarian cancer business |
| Zdroj: | BJOG: An International Journal of Obstetrics & Gynaecology. 127:1409-1420 |
| ISSN: | 1471-0528 1470-0328 |
| Popis: | OBJECTIVE Investigate the clinical landscape of ovarian carcinoma (OC) over time. DESIGN Register-based prospectively collected data. SETTING South East Scotland. SAMPLE A total of 2805 OC patients diagnosed in 1981-2015. METHODS Survival times were visualised using the Kaplan-Meier method; median survival, 5-year survival probabilities and associated restricted mean survival time analyses were used to quantify survival differences. MAIN OUTCOME MEASURES Disease-specific survival. RESULTS A significant increase in disease-specific survival (DSS) from 1981-1985 to 2011-2015 was observed (median 1.73 versus 4.23 years, P |
| Databáze: | OpenAIRE |
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