Impact of a Community-Based Weight Loss Program on Renal Function
| Autor: | Bobbie Paull-Forney, Georges Elhomsy, Tiffany E Schwasinger-Schmidt |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
obesity nutrition and metabolism hypertension Blood sugar Renal function 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine improved ckd stage Weight loss Diabetes mellitus Internal medicine Weight management Internal Medicine Medicine kidney function business.industry General Engineering Endocrinology/Diabetes/Metabolism lifestyle intervention medicine.disease community based weight loss intervention Blood pressure diabetes mellitus medicine.symptom weight loss business behavioral change in weight loss Body mass index 030217 neurology & neurosurgery Family/General Practice Kidney disease |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| Popis: | Introduction Obesity is associated with increased morbidity and mortality and is an independent risk factor for the development and progression of chronic kidney disease (CKD). This study investigated the effect of a community-based, lifestyle-focused, weight-loss intervention on renal function among participants at baseline following 12 weeks of therapy. Methods A retrospective analysis of adults enrolled in a weight management program from 2009 to 2014 was conducted. Participants consumed at least 800 kilocalories per day in meal replacements, attended weekly behavioral education classes, and expended approximately 300 kilocalories per day in physical activity. The primary outcome was the association of weight loss and changes in glomerular filtration rate (GFR). Secondary outcomes included changes in blood sugar levels, lipid parameters, blood pressure, and the use of medication for hypertension and diabetes mellitus. Results Of the 71 participants, 63.4% were female, the average weight was 289 pounds, the average body mass index (BMI) of 53, and baseline GFR 47 ml/min/1.73m2. Following 12 weeks of the intervention, 76.1% of participants improved in CKD stage, 22.4% remained within the same stage, and 1.5% progressed to a higher stage (3A to 3B). Analysis revealed a correlation between weight loss and improved GFR (p=0.0006). Improvements were noted in blood sugar levels, blood pressure, and lipids (p |
| Databáze: | OpenAIRE |
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