Diagnostic performance of qualitative and quantitative shear wave elastography in differentiating malignant from benign breast masses, and association with the histological prognostic factors
| Autor: | Kobkun Muangsomboon, Pornpim Korpraphong, Piyanuch Chitchumnong, Wipawan Apiwat, Nattinee Tretipwanit, Panitta Sitthinamsuwan, Voraparee Suvannarerg, Lassanun Lertdamrongdej, Pongthep Pisarnturakit, Shanigarn Thiravit |
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| Rok vydání: | 2019 |
| Předmět: |
Shear wave elastography
medicine.medical_specialty Optimal cutoff business.industry Ultrasound medicine.disease Gray scale ultrasound 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Breast cancer 030220 oncology & carcinogenesis Needle biopsy Medicine Original Article Radiology Nuclear Medicine and imaging Radiology Elasticity (economics) business |
| Zdroj: | Quantitative Imaging in Medicine and Surgery. 9:386-398 |
| ISSN: | 2223-4306 2223-4292 |
| DOI: | 10.21037/qims.2019.03.04 |
| Popis: | BACKGROUND: To determine the diagnostic performance of qualitative and quantitative shear wave elastography (SWE) and the optimal cutoff values of the quantitative SWE parameters in differentiating malignant from benign breast masses, and to evaluate the association between the quantitative SWE parameters and histological prognostic factors. METHODS: A gray scale ultrasound and SWE were prospectively performed on a total of 244 breast masses (148 benign, and 96 malignant) in 228 consecutive patients before an ultrasound-guided needle biopsy. The qualitative SWE and quantitative SWE parameters (the mean elasticity, maximum elasticity, and elasticity ratio) were measured in each mass. The diagnostic performance of SWE and the optimal cutoff values of the quantitative SWE parameters were obtained. An association analysis of the parameters and histological prognostic factors was performed. RESULTS: The malignant masses had a more heterogeneous pattern on the qualitative SWE than benign masses (P0.05). CONCLUSIONS: The qualitative and quantitative SWE provided good diagnostic performance in differentiating malignant and benign masses. The maximum elasticity of the quantitative SWE parameters had the best diagnostic performance. Adding the three combined quantitative SWE parameters to the BI-RADS category 4A masses potentially downgraded them to BI-RADS category 3 and avoided unnecessary biopsies. No statistically significant association was found between the quantitative SWE parameters and the histological prognostic factors. |
| Databáze: | OpenAIRE |
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