Oxidative Stress in Parkinson’s Disease: Potential Benefits of Antioxidant Supplementation
| Autor: | Aline da Silva Barbosa, Michelli Erica Souza Ferreira, Sandro Percário, Everton Luiz Pompeu Varela, Thayana de Nazaré Araújo Moreira, Maria Fani Dolabela, Antônio Rafael Quadros Gomes |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Aging
Parkinson's disease Antioxidant Reactive oxygen species metabolism Ubiquinone medicine.medical_treatment Population Review Article Disease Bioinformatics medicine.disease_cause Biochemistry Antioxidants Phenols Animals Humans Medicine education education.field_of_study QH573-671 Superoxide Dismutase Terpenes business.industry Parkinson Disease Cell Biology General Medicine medicine.disease Oxidative Stress Life expectancy Reactive Oxygen Species Cytology business Oxidative stress |
| Zdroj: | Oxidative Medicine and Cellular Longevity, Vol 2020 (2020) Oxidative Medicine and Cellular Longevity |
| ISSN: | 1942-0994 1942-0900 |
| DOI: | 10.1155/2020/2360872 |
| Popis: | Parkinson’s disease (PD) occurs in approximately 1% of the population over 65 years of age and has become increasingly more common with advances in age. The number of individuals older than 60 years has been increasing in modern societies, as well as life expectancy in developing countries; therefore, PD may pose an impact on the economic, social, and health structures of these countries. Oxidative stress is highlighted as an important factor in the genesis of PD, involving several enzymes and signaling molecules in the underlying mechanisms of the disease. This review presents updated data on the involvement of oxidative stress in the disease, as well as the use of antioxidant supplements in its therapy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text