Strokes After Cardiac Surgery and Relationship to Carotid Stenosis
| Autor: | Qiang Li, Claranne Mathiesen, John E. Castaldo, Yuebing Li, Donna Jenny, Debra Walicki, James F. Reed, Yevgeniy Isayev |
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| Rok vydání: | 2009 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Comorbidity Risk Assessment Asymptomatic Cohort Studies Postoperative Complications Clinical Protocols Arts and Humanities (miscellaneous) Aortic valve replacement Risk Factors medicine Humans Carotid Stenosis cardiovascular diseases Cardiac Surgical Procedures Stroke Aged Retrospective Studies Endarterectomy Endarterectomy Carotid business.industry Incidence Brain Retrospective cohort study Middle Aged medicine.disease Magnetic Resonance Imaging Cardiac surgery Surgery Causality Stenosis medicine.anatomical_structure cardiovascular system Female Neurology (clinical) medicine.symptom Tomography X-Ray Computed business Artery |
| Zdroj: | Archives of Neurology. 66 |
| ISSN: | 0003-9942 |
| DOI: | 10.1001/archneurol.2009.114 |
| Popis: | Objective To critically examine the role of significant carotid stenosis in the pathogenesis of postoperative stroke following cardiac operations. Design Retrospective cohort study. Setting Single tertiary care hospital. Participants A total of 4335 patients undergoing coronary artery bypass grafting, aortic valve replacement, or both. Main Outcome Measures Incidence, subtype, and arterial distribution of stroke. Results Clinically definite stroke was detected in 1.8% of patients undergoing cardiac operations during the same admission. Only 5.3% of these strokes were of the large-vessel type, and most strokes (76.3%) occurred without significant carotid stenosis. In 60.0% of cases, strokes identified via computed tomographic head scans were not confined to a single carotid artery territory. According to clinical data, in 94.7% of patients, stroke occurred without direct correlation to significant carotid stenosis. Undergoing combined carotid and cardiac operations increases the risk of postoperative stroke compared with patients with a similar degree of carotid stenosis but who underwent cardiac surgery alone (15.1% vs 0%; P = .004). Conclusions There is no direct causal relationship between significant carotid stenosis and postoperative stroke in patients undergoing cardiac operations. Combining carotid and cardiac procedures is neither necessary nor effective in reducing postoperative stroke in patients with asymptomatic carotid stenosis. |
| Databáze: | OpenAIRE |
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