The risk for malignancy using the Milan salivary gland classification categories: A 5-year retrospective review
| Autor: | Jing Liu, Hui Zhu, Christine A Liang, Songlin Zhang, Jaiyeola Thomas Ogunniyi |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Fine-needle aspiration
medicine.medical_specialty Retrospective review Suspicious for Malignancy medicine.diagnostic_test Salivary gland business.industry lcsh:Cytology education salivary gland Milan classification Malignancy medicine.disease Pathology and Forensic Medicine medicine.anatomical_structure risk for malignancy Cytology medicine Atypia Neoplasm Radiology lcsh:QH573-671 business Research Article |
| Zdroj: | CytoJournal CytoJournal, Vol 16, Iss 1, Pp 14-14 (2019) |
| ISSN: | 0974-5963 |
| Popis: | Aims:Since the six-tier Milan salivary gland classification has been introduced, there are very limited studies in literature reporting the risk stratification of the Milan classification.Methods:We retrospectively classified a total of 285 salivary gland cytology cases into Milan reporting categories; there were 23 (8.1%) nondiagnostic, 48 (16.8%) nonneoplastic, 19 (6.7%) atypia of undetermined significance (AUS), 138 (48.4%) benign neoplasm, 13 (4.6%) neoplasm of uncertain malignant potential (NUMP), 8 (2.8%) suspicious for malignancy, and 36 (12.6%) malignant. Almost 110 cases (38.6%) had surgical follow-up resections.Results:The overall risk for malignancy (ROM) was 12.5% for AUS, 3.2% for benign neoplasm, 72.7% for NUMP, and 100% for the suspicious for malignancy and malignant. The ROM for nondiagnostic and nonneoplastic categories was not representative due to limited follow-up resections. The salivary cytology had sensitivity, specificity, positive predictive value, and negative predictive value of 93.0%, 100%, 100%, and 46.2% for neoplasm and 82.3%, 95.8%, 90.3%, and 92.0% for malignant.Conclusion:Our study supports the adaptation of the six-tier Milan classification for reporting salivary gland cytology, as well as emphasizing the utility of the NUMP category. |
| Databáze: | OpenAIRE |
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