Validation of the 2014 European Society of Cardiology Sudden Cardiac Death Risk Prediction Model in Hypertrophic Cardiomyopathy in a Reference Center in South America

Autor: Adrián Fernández, M. Mysuta, Marcelo Biagetti, N. Galizio, E Guevara, Alejandro Quiroga, Agostina M. Fava, Liliana E. Favaloro, José Horacio Casabé, Juan Pablo Ochoa
Rok vydání: 2016
Předmět:
Zdroj: The American Journal of Cardiology. 118:121-126
ISSN: 0002-9149
DOI: 10.1016/j.amjcard.2016.04.021
Popis: Sudden cardiac death (SCD) is a common cause of death in hypertrophic cardiomyopathy (HC). Our aim was to conduct an external and independent validation in South America of the 2014 European Society of Cardiology (ESC) SCD risk prediction model to identify patients requiring an implantable cardioverter defibrillator. This study included 502 consecutive patients with HC followed from March, 1993 to December, 2014. A combined end point of SCD or appropriate implantable cardioverter defibrillator therapy was assessed. For the quantitative estimation of individual 5-year SCD risk, we used the formula: 1 - 0.998(exp(Prognostic index)). Our database also included the abnormal blood pressure response to exercise as a risk marker. We analyzed the 3 categories of 5-year risk proposed by the ESC: low risk (LR)
Databáze: OpenAIRE