Validation of the 2014 European Society of Cardiology Sudden Cardiac Death Risk Prediction Model in Hypertrophic Cardiomyopathy in a Reference Center in South America
Autor: | Adrián Fernández, M. Mysuta, Marcelo Biagetti, N. Galizio, E Guevara, Alejandro Quiroga, Agostina M. Fava, Liliana E. Favaloro, José Horacio Casabé, Juan Pablo Ochoa |
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Rok vydání: | 2016 |
Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Population Cardiomyopathy 030204 cardiovascular system & hematology Risk Assessment Sudden cardiac death Electrocardiography Young Adult 03 medical and health sciences 0302 clinical medicine Predictive Value of Tests Internal medicine medicine Humans 030212 general & internal medicine education Aged Retrospective Studies education.field_of_study business.industry Hypertrophic cardiomyopathy Retrospective cohort study Cardiomyopathy Hypertrophic Middle Aged South America Implantable cardioverter-defibrillator medicine.disease Defibrillators Implantable Death Sudden Cardiac ROC Curve Predictive value of tests Cardiology Female Cardiology and Cardiovascular Medicine business Risk assessment |
Zdroj: | The American Journal of Cardiology. 118:121-126 |
ISSN: | 0002-9149 |
DOI: | 10.1016/j.amjcard.2016.04.021 |
Popis: | Sudden cardiac death (SCD) is a common cause of death in hypertrophic cardiomyopathy (HC). Our aim was to conduct an external and independent validation in South America of the 2014 European Society of Cardiology (ESC) SCD risk prediction model to identify patients requiring an implantable cardioverter defibrillator. This study included 502 consecutive patients with HC followed from March, 1993 to December, 2014. A combined end point of SCD or appropriate implantable cardioverter defibrillator therapy was assessed. For the quantitative estimation of individual 5-year SCD risk, we used the formula: 1 - 0.998(exp(Prognostic index)). Our database also included the abnormal blood pressure response to exercise as a risk marker. We analyzed the 3 categories of 5-year risk proposed by the ESC: low risk (LR) |
Databáze: | OpenAIRE |
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