Resonant electron capture by uridine and deoxyuridine molecules: Fragmentation with charge transfer
| Autor: | Mars V. Muftakhov, P. V. Shchukin |
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| Rok vydání: | 2019 |
| Předmět: |
Anions
Ions Quantitative Biology::Biomolecules Chemistry Electron capture 010401 analytical chemistry Organic Chemistry Electrons Deoxyuridine 01 natural sciences Electron transport chain Mass Spectrometry 0104 chemical sciences Analytical Chemistry Ion Electron Transport chemistry.chemical_compound Fragmentation (mass spectrometry) Chemical physics Intramolecular force Molecule Density functional theory Uridine Spectroscopy |
| Zdroj: | Rapid Communications in Mass Spectrometry. 33:482-490 |
| ISSN: | 0951-4198 |
| DOI: | 10.1002/rcm.8354 |
| Popis: | RATIONALE Charge transfer via DNA plays an important role in physical and chemical processes in biological systems, and is used in biomolecular electronics. The present study considers the resonant interaction of free electrons with nucleosides, which is important for an understanding of the processes of electron transport in DNA. METHODS Resonant electron capture negative ion mass spectrometry was used to study the processes of low-energy electron attachment to two uracil nucleosides, uridine and deoxyuridine, while density functional theory (DFT) calculations were used to analyze the energy aspects of ion formation and decay. RESULTS Short-lived molecular ions, formed via mechanisms of π* shape resonances, were found in the energy region below 5 eV. The fragmentation channels of these resonances and the structures of the charged and neutral products formed were determined. CONCLUSIONS These results suggest that the formation of some fragment negative ions occurs through intramolecular charge transfer. |
| Databáze: | OpenAIRE |
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