Evaluation of the Influence of Sulfur-Fumigated Paeoniae Radix Alba on the Quality of Si Wu Tang by Chromatographic and Chemometric Analysis
| Autor: | Xiao-qing Song, Kai-Lei Fan, Hao Cai, Yu Duan, Feng-xian Qiao, Sicong Tu, Xiao Liu, Baochang Cai, Ke Pei, Xiaoli Wang |
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| Rok vydání: | 2015 |
| Předmět: |
Chromatography
lcsh:QD71-142 Traditional medicine Article Subject 010405 organic chemistry General Chemical Engineering 010401 analytical chemistry lcsh:Analytical chemistry chemistry.chemical_element Paeoniflorin 01 natural sciences Sulfur 0104 chemical sciences Computer Science Applications Analytical Chemistry chemistry.chemical_compound Paeoniae Radix chemistry Si-wu-tang Chemical constituents Chromatographic fingerprint Gallic acid Instrumentation Research Article |
| Zdroj: | Journal of Analytical Methods in Chemistry Journal of Analytical Methods in Chemistry, Vol 2016 (2016) |
| ISSN: | 2090-8865 |
| Popis: | An accurate and reliable method of high-performance liquid chromatographic fingerprint combining with multi-ingredient determination was developed and validated to evaluate the influence of sulfur-fumigatedPaeoniae Radix Albaon the quality and chemical constituents of Si Wu Tang. Multivariate data analysis including hierarchical cluster analysis and principal component analysis, which integrated with high-performance liquid chromatographic fingerprint and multi-ingredient determination, was employed to evaluate Si Wu Tang in a more objective and scientific way. Interestingly, in this paper, a total of 37 and 36 peaks were marked as common peaks in ten batches of Si Wu Tang containing sun-driedPaeoniae Radix Albaand ten batches of Si Wu Tang containing sulfur-fumigatedPaeoniae Radix Alba, respectively, which indicated the changed fingerprint profile of Si Wu Tang when containing sulfur-fumigated herb. Furthermore, the results of simultaneous determination for multiple ingredients showed that the contents of albiflorin and paeoniflorin decreased significantly (P<0.01) and the contents of gallic acid andZ-ligustilide decreased to some extent at the same time when Si Wu Tang contained sulfur-fumigatedPaeoniae Radix Alba. Therefore, sulfur-fumigation processing may have great influence on the quality of Chinese herbal prescription. |
| Databáze: | OpenAIRE |
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