Lacking evidence for the association between frequent urine drug screening and health outcomes of persons on opioid agonist therapy
| Autor: | Lauren Gorfinkel, Eloise Moss, Jan Klimas, Evan Wood, Lauren Adye-White, Walter Cullen, Kelsey C. Priest, Jasmine McEachern |
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| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Urine drug screening Urinalysis medicine.diagnostic_test business.industry Substance-Related Disorders Health Policy MEDLINE Medicine (miscellaneous) Context (language use) Opioid use disorder medicine.disease Health outcomes Opioid-Related Disorders Article Treatment Outcome Opioid Agonist medicine Humans Mass Screening In patient Drug Monitoring Intensive care medicine business |
| Zdroj: | The International journal on drug policy. 64 |
| ISSN: | 1873-4758 |
| Popis: | Background Opioid agonist therapy (OAT) is a first-line treatment for opioid use disorder (OUD); however, the efficacy and role of urine drug screening (UDS) in OAT has received little research attention. Prior evidence suggests that UDS frequency reflects philosophy and practice context rather than differences in patient characteristics or clinical need. Therefore, we reviewed the literature on the effect of and recommendations for the frequency of UDS on health outcomes for persons with OUD who receive OAT. Methods We searched Medline and EMBASE for articles published from 1995-2017. Search results underwent double, independent review with discrepancies resolved through discussion with a third reviewer, when necessary. Additional articles were identified through snowball searching, hand searching (Google Scholar), and expert consultation. The Cochrane tool was used to assess risk of bias. Results Of the 60 potentially eligible articles reviewed, only one three-arm randomized open-label trial, comparing weekly and monthly UDS testing with take-home OAT doses, met our inclusion criteria. Conclusions Our review identified an urgent gap in research evidence underpinning an area of clinical importance and that is routinely reported by patients as an area of concern. |
| Databáze: | OpenAIRE |
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