Ram seminal plasma and its functional proteomic assessment
Autor: | J.P. Rickard, Xavier Druart, T. Leahy, S.P. de Graaf, Naomi C. Bernecic |
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Přispěvatelé: | Faculty of Science, School of Life and Environmental Sciences, University of Sydney, Physiologie de la reproduction et des comportements [Nouzilly] (PRC), Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS), Australian Wool Innovation, NSW Stud Merino Breeders Association Trust, Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours-Centre National de la Recherche Scientifique (CNRS) |
Rok vydání: | 2019 |
Předmět: |
Male
0301 basic medicine Embryology Proteome Seminal Plasma Proteins [SDV]Life Sciences [q-bio] Reproductive technology Biology 03 medical and health sciences 0302 clinical medicine Endocrinology medicine Animals [INFO]Computer Science [cs] Fertilisation Physiological function Sheep 030219 obstetrics & reproductive medicine Spermatozoon urogenital system Obstetrics and Gynecology Cell Biology Spermatozoa Sperm Cell biology 030104 developmental biology medicine.anatomical_structure Reproductive Medicine Function (biology) |
Zdroj: | Reproduction-Cambridge-Supplement Reproduction-Cambridge-Supplement-, Society for Reproduction and Fertility, 2019, 157 (6), pp.R243-R256. ⟨10.1530/REP-18-0627⟩ |
ISSN: | 1741-7899 1470-1626 1477-0415 |
DOI: | 10.1530/rep-18-0627 |
Popis: | Ejaculation results in the confluence of epididymal spermatozoa with secretions of the accessory sex glands. This interaction is not a prerequisite for fertilisation success, but seminal factors do play a crucial role in prolonging the survival of spermatozoa bothin vitroandin vivoby affording protection from handling induced stress and some selective mechanisms of the female reproductive tract. Reproductive biologists have long sought to identify specific factors in seminal plasma that influence sperm function and fertility in these contexts. Many seminal plasma proteins have been identified as diagnostic predictors of sperm function and have been isolated and appliedin vitroto prevent sperm damage associated with the application of artificial reproductive technologies. Proteomic assessment of the spermatozoon, and its surroundings, has provided considerable advances towards these goals and allowed for greater understanding of their physiological function. In this review, the importance of seminal plasma will be examined through a proteomic lens to provide comprehensive analysis of the ram seminal proteome and detail the use of proteomic studies that correlate seminal plasma proteins with ram sperm function and preservation ability. |
Databáze: | OpenAIRE |
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