Association of bone mineral density with bone texture attributes extracted using routine magnetic resonance imaging
| Autor: | Francisco José Albuquerque de Paula, Lucio C. Trazzi, Carlos Ernesto Garrido Salmon, Marcello Henrique Nogueira-Barbosa, Jamilly Gomes Maciel, Iana Mizumukai de Araújo, Paulo Mazzoncini de Azevedo-Marques |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Medicine (General)
Bone density Concordance Lumbar vertebrae 030204 cardiovascular system & hematology Bone Mineral Density 03 medical and health sciences symbols.namesake 0302 clinical medicine R5-920 Absorptiometry Photon Bone Density Linear regression medicine Humans 030212 general & internal medicine DENSIDADE ÓSSEA Mathematics Bone mineral Lumbar Vertebrae medicine.diagnostic_test business.industry Reproducibility of Results Textural Attribute Magnetic resonance imaging General Medicine Magnetic Resonance Imaging Pearson product-moment correlation coefficient Confidence interval medicine.anatomical_structure symbols Original Article Nuclear medicine business |
| Zdroj: | Clinics; v. 75 (2020); e1766 Clinics; Vol. 75 (2020); e1766 Clinics Universidade de São Paulo (USP) instacron:USP Clinics, Vol 75 (2020) Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) |
| ISSN: | 1980-5322 1807-5932 |
| Popis: | OBJECTIVE: Dual-energy X-ray absorptiometry (DXA)-derived bone mineral density (BMD) often fails to predict fragility fractures. Quantitative textural analysis using magnetic resonance imaging (MRI) may potentially yield useful radiomic features to predict fractures. We aimed to investigate the correlation between BMD and texture attributes (TAs) extracted from MRI scans and the interobserver reproducibility of the analysis. METHODS: Forty-nine volunteers underwent lumbar spine 1.5-T MRI and DXA. Three-dimensional (3-D) gray-level co-occurrence matrices were measured from routine sagittal T2 fast spin-echo images using the IBEX software. Twenty-two TAs were extracted from 3-D segmented L3 vertebrae. The estimated concordance coefficient was calculated using linear regression analysis. A Pearson correlation coefficient analysis was performed to evaluate the correlation between BMD and the TAs. Interobserver reproducibility was assessed with the concordance coefficient described by Lin. RESULTS: The results revealed a fair-to-moderate significant correlation between BMD and 13 TAs (r=−0.20 to 0.39; p |
| Databáze: | OpenAIRE |
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