Interactive effect of sarcopenia and falls on vertebral osteoporotic fracture in patients with rheumatoid arthritis
| Autor: | Jing-Jing Tong, Ke-Ming Chen, Yu-Zhu Teng, Shengqian Xu, Jian-Xiong Wang, He-Xiang Zong, Yi-Ran Chu |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Bone mineral
Sarcopenia medicine.medical_specialty business.industry Incidence (epidemiology) Osteoporosis medicine.disease Gastroenterology Arthritis Rheumatoid Bone Density Risk Factors Rheumatoid arthritis Internal medicine Orthopedic surgery Humans Spinal Fractures Medicine Orthopedics and Sports Medicine Risk factor business Bioelectrical impedance analysis Osteoporotic Fractures Aged |
| Zdroj: | Archives of Osteoporosis. 16 |
| ISSN: | 1862-3514 1862-3522 |
| DOI: | 10.1007/s11657-021-01017-1 |
| Popis: | Patients with rheumatoid arthritis (RA) had higher incidences of sarcopenia, falls, osteoporosis, and vertebral osteoporotic fractures (VOPF). Sarcopenia was associated with longer disease duration, higher disease activity, and more severe RA. The interactive effect of sarcopenia and falls was associated with a higher risk of VOPF in patients with RA. Whether sarcopenia and falls are a risk factor for vertebral fracture in RA patients has not been demonstrated. This study aimed to explore the incidence of vertebral osteoporotic fracture (VOPF) and its relationship with sarcopenia and falls in RA patients. A total of 474 RA patients and 156 controls were enrolled in this study. Anteroposterior and lateral X-ray examinations of the vertebral column (T4-L4) were used for the semiquantitative assessment of VOPF. Bone mineral density was measured by dual-energy X-ray absorptiometry. Skeletal muscle mass was measured by direct segmental multifrequency bioelectrical impedance analysis (DSM-BIA method). RA patients had an increased risk of sarcopenia (62.4% vs 9.0%, x2 = 47.478, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink