Immunoscintigraphy using different methods of applying a 99mTc labeled monoclonal anti-CEA-antibody in the staging of patients with liver metastases before partial hepatectomy
| Autor: | D. L. Munz, N. Rilinger, H.J. Halbfaβ, H. J. Illiger, H. Niemann |
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| Rok vydání: | 1991 |
| Předmět: |
Adult
medicine.medical_specialty medicine.drug_class chemistry.chemical_element Technetium Scintigraphy Monoclonal antibody 030218 nuclear medicine & medical imaging Immunoscintigraphy 03 medical and health sciences 0302 clinical medicine Carcinoembryonic antigen medicine Hepatectomy Humans Radionuclide Imaging Aged Neoplasm Staging medicine.diagnostic_test biology business.industry Anti-CEA Antibody Liver Neoplasms Antibodies Monoclonal General Medicine Middle Aged Carcinoembryonic Antigen 3. Good health Injections Intra-Arterial chemistry 030220 oncology & carcinogenesis Injections Intravenous Angiography Monoclonal biology.protein Radiology Colorectal Neoplasms business |
| Zdroj: | International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology. 18:65-68 |
| ISSN: | 0883-2897 |
| Popis: | It was the aim of this study to determine the value of portal-venous (p.v.), intra-arterial (i.a.) or intravenous (i.v.) IS in the detection of liver metastases. Immediately after angiography and i.a. CT (20 patients) or p.v. CT (6 patients), 0.7–1.2 GBq of the 99mTc labeled anti-CEA MoAb were injected via the i.a. catheter, and in 10 patients i.v. Planar scanning was performed. Using IS in the detection of liver metastases a total sensitivity of 61% was established. However, IS was still found to be the decisive method of excluding extrahepatic tumor deposits. |
| Databáze: | OpenAIRE |
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