Gauging Gait Disorders with a Method Inspired by Motor Control Theories: A Pilot Study in Friedreich’s Ataxia
| Autor: | Samantha Norman, Stephanie Salabarria, S. H. Subramony, Bryanna Sharot, Manuela Corti, Arnaud Gouelle |
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| Přispěvatelé: | Performance, Santé, Métrologie, Société - EA 7507 (PSMS), Université de Reims Champagne-Ardenne (URCA) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Ataxia Population Pilot Projects Walking lcsh:Chemical technology Biochemistry Article Analytical Chemistry 03 medical and health sciences 0302 clinical medicine Gait (human) Physical medicine and rehabilitation medicine Humans lcsh:TP1-1185 Electrical and Electronic Engineering [PHYS.MECA.BIOM]Physics [physics]/Mechanics [physics]/Biomechanics [physics.med-ph] education Set (psychology) Instrumentation Gait gait scores education.field_of_study pressure walkway variability Motor control Neurodegenerative Diseases 030229 sport sciences organization walk ratio Atomic and Molecular Physics and Optics Friedreich Ataxia Gait analysis Scale (social sciences) Normative medicine.symptom Psychology 030217 neurology & neurosurgery |
| Zdroj: | Sensors, Vol 21, Iss 1144, p 1144 (2021) Sensors Sensors, MDPI, 2021, 21 (4), pp.1144. ⟨10.3390/s21041144⟩ Sensors (Basel, Switzerland) Volume 21 Issue 4 |
| ISSN: | 1424-8220 |
| DOI: | 10.3390/s21041144⟩ |
| Popis: | International audience; To date, it has been challenging for clinicians and researchers alike to use the multiple outcome measures available to create a meaningful clinical picture and perform effective longitudinal follow-up. It has been found that instrumented gait analysis can provide information associated with a patient’s performance and help to remedy the shortcomings of the currently available outcome measures. The goal of this methodological article is to set the background and justify a new outcome measure inspired by the motor control theories to analyze gait using spatiotemporal parameters. The method is applied in a population of individuals living with Friedreich’s ataxia (FRDA), a neurodegenerative disease. The sample population consisted of 19 subjects, 11 to 65 years of age with FRDA, who either ambulated independently, with a cane, or with a rollator. Three scores based on the distance from healthy normative data were used: Organization Score, Variability Score, and an overall measurement, the Global Ambulation Score. The scores were then compared to the Scale for Assessment and Rating of Ataxia (SARA) Gait Score (SARA-GS), a clinical scale currently being used for gait analysis in FRDA. Organization Scores demonstrated a longitudinal deterioration in the gait characteristics from independent ambulators to those who ambulated with a rollator. Variability Scores mostly reflected dynamic instability, which became greater as the requirement of an ambulation aid or the switch from a cane to a rollator was imminent. The global value given by the Global Ambulation Score, which takes into consideration both the Organization Score, the Variability Score, and the level of assistive device, demonstrated a logarithmic relationship with the SARA-GS. Overall, these results highlight that both components introduced should be analyzed concurrently and suggest that the Global Ambulation Score may be a valuable outcome measure for longitudinal disease progression. |
| Databáze: | OpenAIRE |
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