The Chemistry and Biology of Nakiterpiosin – C-nor-D-Homosteroids

Autor: Lawrence G. Lum, Brett Lomenick, Lih Wen Deng, Qiaoling Wang, Chih Wei Fan, Shuanhu Gao, Jing Huang, Jie Liu, Gelin Wang, Chuo Chen
Rok vydání: 2012
Předmět:
Zdroj: Synlett. 23:2298-2310
ISSN: 1437-2096
0936-5214
DOI: 10.1055/s-0031-1290460
Popis: Isolated from the sponge Terpios hoshinota that causes coral black disease, nakiterpiosin was the first C-nor-D-homosteroid discovered from a marine source. We provide in this account an overview of the chemistry and biology of this natural product. We also include a short history of the synthesis of C-nor-D-homosteroids and the results of some unpublished biological studies of nakiterpiosin.
Databáze: OpenAIRE