Fatigue, Anxiety, and Quality of Life in Breast Cancer Patients Compared to Non-Cancer Controls: a Nationwide Longitudinal Analysis
| Autor: | Ann M. O'Mara, Victor Kipnis, Jerry W. Mitchell, Amber S. Kleckner, Charles S. Kamen, Luke J. Peppone, AnnaLynn M Williams, Jodi Geer, Carly Paterson Khan, Karen Mustian, Shaker R. Dakhil, Michelle C Janelsins, C. E. Heckler, Mary Ontko, Debra L. Barton |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Cancer Research medicine.medical_specialty medicine.medical_treatment Psychological intervention Breast Neoplasms Anxiety Article 03 medical and health sciences 0302 clinical medicine Breast cancer Quality of life Internal medicine Survivorship curve Medicine Humans Fatigue Mastectomy business.industry Depression Cancer medicine.disease 030104 developmental biology Oncology 030220 oncology & carcinogenesis Quality of Life Marital status Female medicine.symptom business |
| Zdroj: | Breast Cancer Res Treat |
| Popis: | PURPOSE: Fatigue and anxiety are common and significant symptoms reported by cancer patients. Few studies have examined the trajectory of multidimensional fatigue and anxiety, the relationships between them and with quality of life. METHODS: Breast cancer patients (n=580) from community oncology clinics and age-matched controls (n=364) completed fatigue and anxiety questionnaires prior to chemotherapy (A1), at chemotherapy completion (A2), and six months post-chemotherapy (A3). Linear mixed models (LMM) compared trajectories of fatigue /anxiety over time in patients and controls and estimated their relationship with quality of life. Models adjusted for age, education, race, BMI, marital status, menopausal status, and sleep symptoms. RESULTS: Patients reported greater fatigue and anxiety compared to controls at all time points (p’s |
| Databáze: | OpenAIRE |
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