Tachycardia, orthostatic hypotension and profound weakness due to concomitant use of fluoxetine and nifedipine
| Autor: | T. L. T. Azaz-Livshits, H. D. Danenberg |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Tachycardia
Heart disease Nifedipine Serotonin reuptake inhibitor Orthostatic vital signs Hypotension Orthostatic Fluoxetine medicine Humans Pharmacology (medical) Drug Interactions Antihypertensive Agents Fatigue Aged Aged 80 and over business.industry Calcium channel General Medicine medicine.disease Calcium Channel Blockers Psychiatry and Mental health Anesthesia Hypertension Drug Therapy Combination Female medicine.symptom business Reuptake inhibitor Selective Serotonin Reuptake Inhibitors medicine.drug |
| Zdroj: | Pharmacopsychiatry. 30(6) |
| ISSN: | 0176-3679 |
| Popis: | The use of the selective serotonin reuptake inhibitor fluoxetine is associated with only minor cardiovascular effects. However, due to a possible inhibitory effect on the metabolism of calcium channel blockers it may potentiate the activity of nifedipine, causing profound adverse cardiovascular effects. This report describes the appearance of profound weakness, orthostatic hypotension and tachycardia following the initiation of fluoxetine treatment in a nifedipine-treated 80-year-old patient. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|