Socioeconomic status is inversely associated with esophageal squamous cell carcinoma risk: results from a population-based case-control study in China
| Autor: | Li Jin, Ziyu Yuan, Hongwei Cheng, Xingdong Chen, Yuechan Zhang, Weimin Ye, Ming Lu, Xiaorong Yang, Chen Suo, Peipei Gao |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Inverse Association case-control study Population multiple correspondence analysis Logistic regression socioeconomic status 03 medical and health sciences 0302 clinical medicine Multiple correspondence analysis Medicine education Socioeconomic status education.field_of_study business.industry Case-control study wealth score Odds ratio Confidence interval esophageal squamous cell carcinoma 030104 developmental biology Oncology 030220 oncology & carcinogenesis business Research Paper Demography |
| Zdroj: | Oncotarget |
| ISSN: | 1949-2553 |
| DOI: | 10.18632/oncotarget.24003 |
| Popis: | Socioeconomic status (SES) is suspected to influence the risk of esophageal squamous-cell carcinoma (ESCC) in China, however, the evidence is still inconclusive and the selection of SES indicators remains inconsistent. In current study, we examined the association between SES and risk of ESCC based on a population-based case-control study in Taixing, China, with 1298 histopathology-confirmed cases and 1900 controls recruited between October 2010 and September 2013. Data on SES indicators was collected using a structured questionnaire. We constructed a composite wealth score based on the ownership of a series of household appliances and other variables by using multiple correspondence analysis (MCA). We used unconditional logistic regression to estimate odds ratios (ORs) with 95% confidence intervals (CIs) of ESCC in association with SES indicators. SES was inversely associated with ESCC risk in current study. Higher education (secondary high school or above vs illiteracy, OR=0.60, 95%CI, 0.41-0.87), larger house area per person (>70 vs 5 years also had a lower ESCC risk. Whereas physical labor (very active vs sedentary, OR=1.69, 95%CI, 1.27-2.26) and larger families (≥6 vs |
| Databáze: | OpenAIRE |
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