Evaluation of Patients with Fibrotic Interstitial Lung Disease: Preliminary results from the Turk-UIP Study

Autor: Müsellim, Benan, Moğulkoç, Nesrin, Uzun, Oğuz, Akyıl, Fatma Tokgöz, Türktaş, Haluk, Kumbasar, Özlem Özdemir, Okumuş, Gülfer, Oğuş, Candan, Dirol, Hülya, Zamani, Adil, Sevim, Tülin, Annakkaya Ali Nihat, Özyürek, Berna Akıncı, Hanta, İsmail, Aydemir, Yusuf, Edis, Ebru Çakır, Kurt, Bahar, Tertemiz, Kemal Can, Tabak, Levent, Yazıcı, Onur, Erdoğan, Yurdanur, Ateş, Güngör, Türker, Hatice, Salepçi, Banu, Hazar, Armağan, Niksarlıoğu, Elif Yelda, Kara, Bilge Yılmaz, Köktürk, Nurdan, Kalpaklıoğlu, Füsun, Uzel, Işıl, Özsu, Savaş, Atahan, Ersan, Fendoğlu, Türkan Zeynep, Süreyya, Yılmaz, Başyiğit, İlknur, Çamsarı, Güngör, Tuncay, Esin, Yılmazel, Elif Uçar, Kanmaz, Dilek, Ekici, Aydanur, Topçu, Füsun, Uzaslan, Esra, Bozkuş, Fülsen, Barış, Serap Argun, Duru, Serap, Altınışık, Göksel, Bingöl, Züleyha, Tunacı, Atadan, Savaş, Recep, Alper, Fatih, Bayraktaroğlu, Selen, Can, Tuba Selçuk, Demir, Ali Arslan
Přispěvatelé: Dicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Göğüs Hastalıkları Ana Bilim Dalı, Topçu, Füsun, Işıl, Uzel, Musellim, Benan, Moğulkoç, Nesrin, Uzun, Oğuz, Tokgöz Akyıl, Fatma, Türktaş, Haluk, Özdemir Kumbasar, Özlem, Okumuş, Gülfer, Öğüş, Candan, Dirol, Hülya, Zamani, Adil, Sevim, Tülin, Annakkaya, Ali Nihat, Özyürek, Berna Akıncı, Hanta, İsmail, Aydemir, Yusuf, Çakır Edis, Ebru, Kurt, Bahar, Tertemiz, Kemal Can, Tabak, Levent, Yazıcı, Onur, Erdoğan, Yurdanur, Ateş, Güngör, Türker, Hatice, Salepçi Banu, Hazar, Armağan, Niksarlıoğlu, Elif Yelda, Yılmaz Kara, Bilge, Köktürk, Nurdan, Kalpaklıoğlu, Füsun, Özsu, Savaş, Atahan, Ersan, Fendoğlu, Türkan Zeynep, Yılmaz Süreyya, Başyiğit İlknur, Çamsarı, Güngör, Tunçay, Esin, Uçar Yılmazel, Elif, Kanmaz, Dilek, Ekici, Aydanur, Topçu Füsun, Uzaslan, Esra, Bozkuş Fulsen, Argun Barış, Serap, Duru, Serap, Altınışık, Göksel, Bingöl, Züleyha, Tunacı, Atadan, Savaş, Recep, Alper, Fatih, Bayraktaroğlu, Selen, Selçuk Can, Tuba, Demir, Ali Arslan, Koç University Hospital, RTEÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kara, Bilge Yılmaz, [Belirlenecek], OMÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Turkish Thoracic Journal
Turk Thorac J
Popis: OBJECTIVE: Differential diagnosis of idiopathic pulmonary fibrosis (IPF) is important among fibrotic interstitial lung diseases (ILD). This study aimed to evaluate the rate of IPF in patients with fibrotic ILD and to determine the clinical-laboratory features of patients with and without IPF that would provide the differential diagnosis of IPF. MATERIAL AND METHODS: The study included the patients with the usual interstitial pneumonia (UIP) pattern or possible UIP pattern on thorax high-resolution computed tomography, and/or UIP pattern, probable UIP or possible UIP pattern at lung biopsy according to the 2011 ATS/ERS/JRS/ALAT guidelines. Demographics and clinical and radiological data of the patients were recorded. All data recorded by researchers was evaluated by radiology and the clinical decision board. RESULTS: A total of 336 patients (253 men, 83 women, age 65.8±9.0 years) were evaluated. Of the patients with sufficient data for diagnosis (n=300), the diagnosis was IPF in 121 (40.3%), unclassified idiopathic interstitial pneumonia in 50 (16.7%), combined pulmonary fibrosis and emphysema (CPFE) in 40 (13.3%), and lung involvement of connective tissue disease (CTD) in 16 (5.3%). When 29 patients with definite IPF features were added to the patients with CPFE, the total number of IPF patients reached 150 (50%). Rate of male sex (p
Roche
Financial Disclosure: This research received unconditional financial support from the company of Roche.
Databáze: OpenAIRE