Sex-Specific Plaque Signature: Uniqueness of Atherosclerosis in Women
Autor: | Ilton M. Cubero Salazar, Brigitte E. Kazzi, Allison G. Hays, Andrew D. Choi, Anum S. Minhas, Erin D. Michos, Armin Arbab-Zadeh |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Male
medicine.medical_specialty Disease Coronary Artery Disease 030204 cardiovascular system & hematology Coronary disease Article Imaging modalities Coronary artery disease 03 medical and health sciences 0302 clinical medicine Sex Factors Risk Factors Internal medicine medicine Humans 030212 general & internal medicine business.industry medicine.disease Atherosclerosis Sex specific Coronary heart disease Plaque Atherosclerotic Cardiology Female Presentation (obstetrics) Cardiology and Cardiovascular Medicine business |
Zdroj: | Curr Cardiol Rep |
Popis: | PURPOSE OF REVIEW: Cardiovascular disease is a leading cause of morbidity and mortality in both men and women, although there are notable differences in presentation between men and women. Atherosclerosis remains the predominant driver of coronary heart disease in both sexes; however, sex differences in atherosclerosis should be investigated further to understand clinical manifestations between men and women. RECENT FINDINGS: There are sex differences in the prevalence, progression, and prognostic impact of atherosclerosis. Furthermore, developing evidence demonstrates unique differences in atherosclerotic plaque characteristics between men and women on both non-invasive and invasive imaging modalities. Coronary microvascular dysfunction may be present even if no obstructive lesions are found. Most importantly, non-obstructive coronary artery disease is associated with a heightened risk of future adverse cardiovascular events and should not be ignored. SUMMARY: The distinct plaque signature in women should be recognized, and optimal preventive strategies should be performed for both sexes. |
Databáze: | OpenAIRE |
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